19^th Euro Obesity and Endocrinology Congress

Genetics of obesity

Obesity is the result of an exchange between behavior, environment, and genetic factors. Studies have recognized development in several genes that may contribute to obesity gain and body fat distribution; while, only in a few cases are genes the primary cause of obesity. Polymorphisms in several genes controlling appetite and metabolism predispose to obese under convinced dietary conditions. The percentage of obesity that can be attributed to genetics varies extensively, depending on the population survey from 6% to 85%.  As of 2006, more than 41 sites on the human genome have been linked to the evolution of obesity when a favorable environment is present. The involvement of genetic factors in the progress of obesity is assessed to be 40–70%. Some of the obesogenic or leptogenic genes may affect obese individual’s response to weight loss or weight management.